Michael Duff is the name of:
Michael Duff (physicist) (born 1949), British theoretical physicist Michael Duff (footballer) (born 1978), Northern Irish international footballer and manager Sir Michael Duff, 3rd Baronet (1907–1980), British statesman and socialite Michael J. B. Duff (1933–2021), British computer scientist and physicist
See also Mickey Duff (1929–2014), British boxer Michelle Duff, (born Michael Allan Duff, 1939), Canadian road racer