Mike Patterson may refer to:
Mike Patterson (American football) (born 1983), American football defensive tackle Mike Patterson (baseball) (born 1958), former Major League Baseball outfielder Mike Patterson (footballer) (1941–2002), Australian rules footballer and coach Mike Patterson (transport director) (fl. 1970s–2010s), director of the Oklahoma Department of Transportation
See also Mike Paterson (born 1942), computer scientist Michael Patterson (disambiguation)