Faccio is a surname. Notable people with the surname include:

Adele Faccio (1920–2007), Italian politician Franco Faccio (1840–1891), Italian opera composer and conductor Nicolas Faccio (1664–1753), Swiss mathematician; alternative name for Nicolas Fatio de Duillier Ricardo Faccio (1907–1970), Uruguayan-Italian football player

See also Facio Fatio