Mahoning Creek may refer to the following creeks in the U.S. state of Pennsylvania:
Mahoning Creek (Allegheny River), a tributary of the Allegheny River Mahoning Creek (Lehigh River), a tributary of the Lehigh River in Lehigh County Mahoning Creek (Susquehanna River), a tributary of the Susquehanna River in Montour County
See also Mahoning River, in Ohio and Pennsylvania