HWB may refer to:
Hwb, a Welsh education website HWB color model, a representation of points in an RGB color model Hardware write block device, a type of computer hard disk controller Hawaii Winter Baseball, a defunct professional baseball league Health and wellbeing board, various statutory bodies in England Heavy Water Board, of India's Department of Atomic Energy Helmert–Wolf blocking, a statistical algorithm Hochwohlgeboren, an honorific in Europe Homeopaths Without Borders, a pseudoscientific nonprofit organization Hybrid wing body, a type of fixed-wing aircraft Herbert Walker Bush