M87 or M-87 may refer to:
Military M87 machine gun, a Yugoslav copy of the NSVT machine gun M-87 Orkan, a Yugoslav rocket-artillery vehicle
Transportation Tumansky M-87, a Soviet aircraft engine M-87 (Michigan highway), a former state highway in Michigan, US McDonnell Douglas MD-87, a passenger airplane
Other uses Messier 87, a giant elliptical galaxy in the Virgo Cluster M87*, a supermassive black hole at Messier 87's core M87 Ray (α and β), the signature move of the character Zoffy from the Ultra Series of television shows; See List of Ultraman Ginga characters "M87", the theme song for the 2022 film Shin Ultraman by Kenshi Yonezu.