RWE may refer to:
RWE AG, German multinational energy company Ralph Waldo Emerson (1803-1882), American lecturer, philosopher, essayist, and poet FC Rot-Weiß Erfurt, German association football club Rot-Weiss Essen, German association football club Read write execute (RWE), basic permissions of a computer file Real world evidence (RWE), observational data obtained outside the context of randomized controlled trials (RCTs) Right-wing extremism, more commonly known as far-right politics Ringwood East railway station, Melbourne Radio Wolna Europa, Polish for Radio Free Europe