Santa Maria Nova or Santa Maria Nuova may refer to:
Churches in Italy Santa Maria Nuova, Cortona Santa Francesca Romana, Rome Santa Maria Nuova, Fano, a church in Fano Monreale Cathedral (), Palermo Santa Maria Nuova, Pistoia Santa Maria Nova, Toffia Santa Maria Nova, Vicenza Santa Maria Nuova, Viterbo
Other Santa Maria Nuova, Marche, a commune in italy
See also Santa Maria La Nova (disambiguation) Hospital of Santa Maria Nuova, Florence, Italy