Michael Gottlieb may refer to:

Michael T. Gottlieb (1900–1980), American bridge player Michael Gottlieb (director) (1945–2014), American film director, screenwriter and video game producer Michael S. Gottlieb (born 1947), American physician and immunologist Michael Gottlieb (politician) (born 1968), American politician and member of the Florida House of Representatives

See also Michael Gottlieb Agnethler (1719–1752), German botanist and numismatist Michael Gottlieb Bindesbøll (1800–1856), Danish architect Michael Gottlieb Birckner (1756–1798), Danish priest and philosopher