Edward Wynne may refer to:

Edward Wynne (colonial administrator), proprietary governor of the Ferryland colony from 1621 to 1626 Edward Wynne (chancellor) (1681–1755), Welsh lawyer and landowner Edward Wynne (jurist) (1734–1784), English lawyer and scholar Ed Wynne (born 1961), English guitarist Ed Wynne (saxophonist), musician with the Doobie Brothers Edward Wynne-Pendarves (1775–1853), British politician

See also Ed Wynn (1886–1966), American actor and comedian Edward Wynn (1889–1956), English bishop William Watkin Edward Wynne (1801–1880), Welsh politician and antiquarian