Megapolis is a variant of the word megalopolis, meaning a large city or urban area.
Megapolis may also refer to: Megapolis (game), a game developed by Social Quantum Ministry of Megapolis, a cabinet of the prime minister in Sri Lanka. Megapolis Festival, an annual audio arts festival in the United States Megapolis (passenger train), a passenger train in Russia Megapolis Zoo, the home of fictional cartoon character Tennessee Tuxedo
See also Our Lady of Darkness, a 1977 book, by Fritz Leiber, that contains a description of 'Megapolisomancy', a fictional occult science.