DRE may refer to:
Dre (album), 2010 by American rapper Soulja Boy Tell 'Em, 2010 Dre (given name) Dr. Dre, American rapper and producer Laura Dre, German-Filipina electronic musician, singer-songwriter and music producer Dre (Tibetan), one of the eight classes of gods and demons in Tibetan Buddhism DRE voting machine Digital rectal examination, in medicine Director of religious education; for example, Directorio Revolucionario Estudiantil, CIA backed anti-Castro group based in Miami Drug Recognition Expert, law enforcement Drug resistant epilepsy, in neurology Dense-rock equivalent, in geology/volcanology