Clayton Center is an unincorporated community located in Clayton County, Iowa, United States.

History The area was settled as a German colony, approximately five miles east of Elkader. In April 1856, the land was surveyed by Lewis Brockman, who established the location as the "southeast quarter of section 8, township 93 north, range 3 west."History of Clayton County 1882 , Chapter XXXVIII: Read Township, page 1072-1073. Clayton Center was then platted on June 27, 1857, by Fred Hartmann.History of Clayton County, Iowa Volume 1, pages 107, 322, 492. Clayton Center's population was 94 in 1902. The population was 162 in 1940.

Education Public schools are operated by the Clayton Ridge Community School District, which formed in 2005 with the merger of the Guttenberg and Garnavillo Community School Districts."REORGANIZATION & DISSOLUTION ACTIONS SINCE 1965-66 ." Iowa Department of Education. Retrieved on February 23, 2019. Students were previously zoned to Garnavillo schools."History." Garnavillo Community School District. May 29, 2000. Retrieved on February 24, 2019.

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