Zykov (masculine) or Zykova (feminine) is a Russian surname. Notable people with the surname include:

Valeri Zykov, Soviet footballer Nikolai Zykov, Soviet and Russian actor, director, artist, designer, puppet-maker and puppeteer Pyotr Zykov, Soviet general Valentin Zykov, Russian ice hockey player

See also Zykov Island, island in Antarctica Zykov Glacier, glacier in Antarctica Danielle Zaikoff, Canadian engineer