Manitou River may refer to:
Manitou River (Manitoulin Island), drains Lake Manitou on Manitoulin Island in Ontario, Canada Manitou River (Seine River), a tributary of the Seine River in Kenora District, Ontario, Canada Manitou River (Quebec) drains into the Gulf of Saint Lawrence in Quebec, Canada Manitou River (Minnesota) drains the North Shore of Lake Superior in Minnesota, United States
See also Little Manitou River Manitou (disambiguation)