Oppel is a surname. Notable people with the surname include:
Albert Oppel (1831–1865), German paleontologist Kenneth Oppel (born 1967), Canadian author Nicolaus Michael Oppel (1782–1820), German naturalist Reinhard Oppel (1878–1941), German composer Richard Oppel (born 1943), American journalist Richard A. Oppel Jr., American journalist Richard Craig Oppel (born 1967), American swimmer Robert Opel (1939–1979), born Robert Oppel before changing his name to Opel, American photographer, art gallery owner, and streaker Thomas Oppel (born 1953), American politician