Mary Lewis may refer to:
Arts and entertainment Mary Lewis (Canadian actress), Canadian actress and filmmaker from Newfoundland Mary Lewis (soprano) (1900–1941), American soprano and actress Mary Edmonia Lewis (1844–1907), American sculptor Mary Jeffreys Lewis (1852–1926), British-born American actress
Government and politics Mary Anne Lewis, Viscountess Beaconsfield, wife of Disraeli Mary Geiger Lewis (born 1958), United States district judge Mary Parker Lewis, political consultant
Science and academics Mary Lewis (archaeologist), British professor of archaeology Mary Butler Lewis (1903–1970), American anthropologist Mary D. Lewis, professor of French history Mary S. Lewis (1934–2017), American musicologist
Other people Mary Lewis Nicotera, American judoka
See also Lewis (surname) Mary Jane Lewis (disambiguation), various people