Smetona is the masculine form of a Lithuanian family name. Its feminine forms are: Smetonienė (married woman or widow) and Smetonaitė (unmarried woman).

The surname may refer to:

Antanas Smetona (1874–1944), Lithuanian intellectual and journalist (born 1961), Lithuanian linguist and professor (born 1945), Lithuanian film and television director and a politician, M.P. See also Lithuanian warship Prezidentas Smetona