Cwm Clydach (Cwm is Welsh for "valley" and Clydach is a popular river name) may refer to:

Places Cwm Clydach, Kidwelly, a site of special scientific interest (SSSI) near Kidwelly, Carmarthenshire Cwm Clydach National Nature Reserve, on the Clydach Gorge in Blaenau Gwent Cwm Clydach RSPB Reserve, near the village of Clydach, Swansea Cwm Clydach, Rhondda Cynon Taf, a community and electoral ward in Rhondda Cynon Taf based around the village of Clydach Vale Cwm Clydach, the Welsh language name for Clydach Vale, a village in Rhondda Cynon Taf Clydach Gorge (Blaenau Gwent), also known as Cwm Clydach

See also Clydach (disambiguation), in particular for rivers with that name