The Netherlands Football League Championship 1921–1922 was contested by 43 teams participating in four divisions. The national champion would be determined by a play-off featuring the winners of the eastern, northern, southern and western football division of the Netherlands. Go Ahead won this year's championship by beating Blauw-Wit Amsterdam, NAC, and Be Quick 1887.
New entrants Eerste Klasse East: Promoted from 2nd Division: Heracles
Eerste Klasse North: Promoted from 2nd Division: Upright
Eerste Klasse South: Promoted from 2nd Division: PSV Eindhoven
Eerste Klasse West: Promoted from 2nd Division: Feijenoord (returning after two seasons of absence) & RCH
Divisions
Eerste Klasse East
Eerste Klasse North
Eerste Klasse South
Eerste Klasse West
Championship play-off
Play-off
Go Ahead won the championship.
References RSSSF Netherlands Football League Championships 1898-1954 RSSSF Eerste Klasse Oost RSSSF Eerste Klasse Noord RSSSF Eerste Klasse Zuid RSSSF Eerste Klasse West