Hartlieb or Hartlib is a German surname. Notable people with the surname include:

Chuck Hartlieb (born 1966), American football player Ernie Hartlieb (born 1979), American ice hockey player Geoff Hartlieb (born 1993), American baseball player Johannes Hartlieb ( 1410–1468), German physician Max von Hartlieb-Walsporn (1883–1959), German army officer Samuel Hartlib ( 1600–1662), East European-born English polymath

Other uses The Advice to Hartlib, a treatise on education written by Sir William Petty as a letter to Samuel Hartlib Hartlib Circle, a correspondence network set up in Europe by Samuel Hartlib