The Dr. H. Huber Block was a historic commercial building in downtown Ottawa, Ohio, United States. Built in 1882, it was erected for Dr. Hubert Huber, a native of Germany who immigrated to the nearby village of Glandorf in 1853. This Italianate three-story brick building is typical of many commercial buildings constructed in villages such as Ottawa in the late nineteenth century: as prosperity increased, building owners sought to rebuild their structures in the style of those in large cities. Besides maintaining a medical practice in the building, Huber also operated a pharmacy on the first story that continued in operation long after his death; the second floor consisted of residential apartments that he rented out to others, and the third floor was used for nearly a century as a meeting place for the local Knights of Columbus lodge.Owen, Lorrie K., ed. Dictionary of Ohio Historic Places. Vol. 2. St. Clair Shores: Somerset, 1999, 1181.

In 1980, the Huber Block was listed on the National Register of Historic Places. It qualified for inclusion because of its well-preserved historic architecture, which was seen as significant in the local community., Ohio Historical Society, 2007. Accessed 2010-07-09. Building was torn down in 2015 due to the 2007 flood damages.

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