LSL is a three letter abbreviation which may refer to:

Sports Leicestershire Senior League, a football competition Leinster Senior League (association football) Leinster Senior League (cricket) Leinster Senior League (rugby union)

Computers Leisure Suit Larry, a series of adult adventure games Linden Scripting Language, a scripting language Logical shift left, a type of bitwise operation Larch Shared Language, a language for algebraic specification of abstract data types

Finance LSL Property Services, a UK-based company Lincoln Savings and Loan Association, the financial institution at the heart of the Keating Five scandal Lesotho loti, currency of the Kingdom of Lesotho by ISO 4217 code

Other uses LSL (gene), a human gene LSL World Initiative, founded by former Prime Minister of Haiti Laurent Lamothe Laminated strand lumber, a type of engineered wood Landing Ship Logistics, an amphibious warfare vessel of the United Kingdom Lead service line, a pipe made of lead that connects between a water main to the water user's location Liberty Shoes Limited, an Indian footwear manufacturer Locomotive Services Limited, a train operator in England Long service leave, an employee vacation payable after long service in Australia and New Zealand Lower Specification Limit, a statistical measure used in a Process Window Index bounded by UCL/LCL and USL/LSL