Flight 405 may refer to:
Mohawk Airlines Flight 405 (1972), crashed on final approach to Albany International Airport, killing 17. Finnair Flight 405 (1978), hijacked, all survived. Indian Airlines Flight 405, hijacked, all survived. USAir Flight 405 (1992), crashed shortly after liftoff from New York City LaGuardia airport, killing 27. IBC Airways Flight 405 (2013), crashed after an in-flight breakup. Dynamic Airways Flight 405 (2015), caught fire but all survived.