Maisuradze (მაისურაძე) is a Georgian surname. Notable people with the surname include:
Grigol Maisuradze (1817–1885), Georgian painter Irakli Maisuradze (born 1988), Georgian footballer Irakli Maysuradze (born 2000), Georgian figure skater Miriani Maisuradze (born 1999), Georgian wrestler Nino Maisuradze (born 1982), Georgian-French chess player Nodari Maisuradze (born 1988), Russian pair skater of Georgian origin