De Groote is a Dutch surname meaning "the big one". It is most common in Flanders and sometimes is concatenated as DeGroote or Degroote. People with this name include:
Jan de Groote (1911–1989), Dutch farmer and politician Koenraad Degroote (born 1959), Belgian politician Melvin De Groote (1895–1963), American chemist and inventor with 925 patents Michael DeGroote (1933–2022), Canadian businessman and philanthropist Michel De Groote (born 1955), Belgian football defender Patrick De Groote (born 1958), Belgian politician :fr:Paul De Groote (1905–1997), Belgian government minister Steven De Groote (1953–1989), South African classical pianist Thierry De Groote (born 1975), Belgian road bicycle racer Wouter Degroote (born 1978), Belgian footballer
See also De Groote Peel National Park, National Park in the Peel, a region in the Southeast of the Netherlands DeGroote School of Business, faculty at McMaster University in Hamilton, Ontario, Canada Michael G. DeGroote School of Medicine, medical school of McMaster University in Hamilton, Ontario, Canada