Holborne is a surname. Notable people with the surname include:
Anthony Holborne (1545–1602), composer of English consort music during the reign of Queen Elizabeth I James Holborne of Menstrie, Scottish soldier during the years of the English Civil War Robert Holborne (died 1647), lawyer, Member of Parliament, attorney-general to Prince of Wales, knighted 1643 William Holborne, officer on the flagship of Admiral Sir Edward Hawke, the Kent, in 1747
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