Ptahmose was High Priest of Ptah in Memphis during the time of Thutmose IV and/or Amenhotep III. He was the son of a Prophet (priest) named Menkheper.K. Bosse-Griffiths, "The Memphite Stela of Merptaḥ and Ptaḥmosĕ", The Journal of Egyptian Archaeology, Vol. 41 (Dec., 1955), pp. 56-63 Ptahmose's son Pahonte would later serve as High Priest of Ptah.D.B. Redford, "The Coregency of Tuthmosis III and Amenophis II", The Journal of Egyptian Archaeology, Vol. 51 (Dec., 1965), pp. 107-122

Ptahmose is mainly attested by a squatting block statue now in the National Archaeological Museum of Florence (inv. 1790), This statue of Ptahmose is also depicted on Johan Zoffany's painting Tribuna of the Uffizi (1772–78). A key to the people and artworks in Zoffany's Tribuna of the Uffizi (no. 60), oneonta.edu, retrieved 17 October 2014 Other monuments of Ptahmose are a round topped, limestone stela on which he is mentioned along with the High Priest of Ptah Ptahmose, son of Thutmose and his brother Meryptah, and possibly another small stela, again in Florence (inv. 2537) which may represent either Ptahmose son of Menkheper or Ptahmose son of Thutmose.

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