Speedball may refer to:
Games Speedball (paintball), a paintball game variant Speedball (video game), a 1988 video game by Bitmap Brothers
Music "Speedball", a song by Black Label Society from 1919 Eternal "Speedball", jazz composition by Lee Morgan, originally appearing on The Gigolo and later on Live at the Lighthouse "Speedball", a song by John Zorn from Naked City "Speedball", a song by Yeat from Lyfestyle
Sports Speedball (American ball game), a combination of handball and soccer Speed-ball, an Egyptian racquet sport Speedball (boxing), a small punching bag used by boxers for training
Other Speedball (drug), a mix of heroin and cocaine, or similar drugs Speedball (art products), an American art products manufacturer Robbie Baldwin, a Marvel Comics superhero known as "Speedball", formerly known as Penance "Speedball" Mike Bailey, a professional wrestler