Prokofiev most commonly refers to Sergei Prokofiev (1891–1953), Russian composer.
Prokofiev, Prokofyev or Prokofieff may also refer to:
Prokofiev (surname) Prokofiev (song), 1991 song by The Damned Prokofiev (crater), on Mercury Sergei O. Prokofieff (Christian esotericist, grandson of Sergei Prokofiev) Gabriel Prokofiev (Composer, grandson of Sergei Prokofiev)