Menichelli is an Italian surname. Notable people with the surname include:
Edoardo Menichelli (1939–2025), Italian Roman Catholic bishop and cardinal Franco Menichelli (1941–2026), Italian gymnast Giampaolo Menichelli (born 1938), Italian footballer Pina Menichelli (1890–1984), Italian actress Roberto Menichelli (born 1963), Italian futsal player and coach
See also 24818 Menichelli, a main-belt asteroid