Buonanno is an Italian surname derived from a medieval given name meaning . Notable people with the surname include:
Alessandra Buonanno (born 1968), Italian-American theoretical physicist Gianluca Buonanno (1966–2016), Italian politician Helena Buonanno Foulkes (born 1964), American businesswoman and politician
See also 73465 Buonanno, a minor planet Bonanno Bonano