Smithfield Historic District may refer to:
Smithfield Historic District (Birmingham, Alabama), listed on the National Register of Historic Places listings in Jefferson County, Alabama Smithfield Historic District (Smithfield, Virginia), listed on the National Register of Historic Places listings in Isle of Wight County, Virginia Downtown Smithfield Historic District, Smithfield, North Carolina, listed on the National Register of Historic Places listings in Johnston County, North Carolina North Smithfield Historic District, Smithfield, North Carolina, listed on the National Register of Historic Places listings in Johnston County, North Carolina
See also Smithfield Farm, Berryville, Virginia, a historic district listed on the NRHP in Virginia Smithfield Road Historic District, North Smithfield, Rhode Island Smithfield (Blacksburg, Virginia), listed on the NRHP in Virginia Smithfield (Rosedale, Virginia), a historic district listed on the NRHP in Virginia