HSOB may refer to one of many things:
El Obeid Airport, in Sudan, has the ICAO code HSOB High School Old Boys the name of many sporting and alumni organisations, among them: Cardiff HSOB RFC, a Welsh rugby union club Christchurch High School Old Boys, a New Zealand football club Douglas High School Old Boys A.F.C., a Manx football club Dunedin High School Old Boys, a defunct New Zealand football club High School Old Boys RFC, a New Zealand rugby union club Invercargill High School Old Boys, a defunct New Zealand football club Melbourne High School Old Boys Association, an Australian sporting and alumni organisation Napier High School Old Boys, a defunct New Zealand football club Newport HSOB RFC, a Welsh rugby union club