The Mohawk Valley region is in the U.S. state of New York.

Mohawk Valley may also refer to:

The valley of the Mohawk River, a major river in the U.S. state of New York The Mohawk Valley formula is a plan for strikebreaking (1936/37) Mohawk Valley (Arizona) Mohawk Valley, California, former name of Mohawk, California Mohawk River (Oregon)