NSC may refer to:
Banking and investment National Sort Code, an Irish bank code Nomura Securities Co, an investment bank
Computing National Software Centre, an Irish organization National Supercomputer Centre in Sweden NetShow Channel, a streaming media system .nsc, the filename extension for NetShow Channel, now called Windows Media Station Network Systems Corporation, a computer product manufacturer NonStop Clusters, an SCO UnixWare add-on package
Education National Senior Certificate, a South African educational certificate Nehru Science Centre, Mumbai, India Nevada State College, a public college in Henderson, Nevada, United States Northern Southland College, a secondary School in Lumsden, New Zealand Yoshimoto New Star Creation, a Japanese comedy school
Government and politics
National Supervisory Commission, the highest supervision and anti-corruption authority of China New Social Contract, a Dutch political party National Science Council, a government body in Taiwan renamed as Ministry of Science and Technology U.S. Army Natick Soldier Center, a research and development center for soldier equipment
National security agencies
National security council, a government body found in many regions National Security Committee (Australia), peak decision-making body for national security in the Australian Government National Security Committee (Ireland), Irish interdepartmental committee on national security
Medicine National Service Center of the US National Cancer Institute National Skin Centre, a Singapore medical facility Neural stem cell, a concept in nervous system Nursing Service Cross, an Australian Honours System medal
Sport and competition Nashville SC, an American soccer team NSC United, an American soccer team National Scholastics Championship, an American quiz bowl competition National Scrabble Championship, now known as the Scrabble Players Championship National Shooting Centre, a British shooting sports complex near Bisley, United Kingdom National Soccer Conference, a conference of the first North American Soccer League National Sporting Club, a British boxing club National Sports Center, an American sports complex National Sports Centre (Isle of Man) National Sports Club of India Nejmeh SC, a Lebanese association football club Nepean Sailing Club, a Canadian sailing club North Star Conference, a defunct North American women's college sports conference Northern Shores Conference, a Michigan high school athletic conference
Transport National Security Cutter, a U.S. Coast Guard ship design Network SouthCentral, a British railway company Norfolk Southern Railway, an American railway company North–South Corridor, Singapore, an expressway in Singapore North Spokane Corridor, a freeway in Spokane, Washington, US
Other uses National Safety Council, an American nonprofit organization National Salvation Committee, a Ukrainian organization National Savings Certificates (India), an Indian Government Savings Bond National Space Centre (England), a British tourist attraction National Space Council, a panel of government and military officials dedicated to the review and improvement of the United States' space programs. National Statistical Commission, an Indian organization Necessary and sufficient condition, a concept in logic Negative sequence component, see Symmetrical components New Safe Confinement, the structure intended to contain the nuclear reactor at Chernobyl, Ukraine North-South Carrier, a Botswana water pipeline Norwegian Space Centre, Norwegian space public activity center renamed as Norwegian Space Agency