Machairophyllum is a genus of plants in the family Aizoaceae. It includes four species native to the Cape Provinces of South Africa.

Species , Plants of the World Online accepted the following species: Machairophyllum albidum Schwantes Machairophyllum bijlii (N.E.Br.) L.Bolus Machairophyllum brevifolium L.Bolus Machairophyllum stayneri L.Bolus

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