Esprit-Saint () is a municipality in Rimouski-Neigette Regional County Municipality in the Bas-Saint-Laurent region of Quebec, Canada. Its population as of the Canada 2021 Census was 340.

The name Esprit-Saint is in honor of the Holy Spirit who is the third person in the Trinity.

History Esprit-Saint was founded in 1972.

Demographics In the 2021 Census of Population conducted by Statistics Canada, Esprit-Saint had a population of living in of its total private dwellings, a change of from its 2016 population of . With a land area of , it had a population density of in 2021.

See also Touladi River List of municipalities in Quebec

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