Perotti is an Italian surname. Notable people with the surname include:
Angelica Le Gru Perotti (1719–1776), Italian painter Diego Perotti (born 1988), Argentine footballer Fulvia Miani Perotti (1844–1931), Italian writer Giovanni Domenico Perotti (1761–1825), Italian composer José Perotti Ronzoni (1898–1956), Chilean sculptor Juan Perotti (born 1992), Argentine footballer Niccolò Perotti (1429–1480), Italian humanist and author Omar Perotti (born 1959), Argentine politician