SC-40 may refer to:

ISO/IEC JTC 1/SC 40, a standardization subcommittee of the ISO/IEC JTC 1 on IT Service Management and IT Governance SC-40, a computer developed by Systems Concepts , a United States Navy submarine chaser commissioned in 1918 and sold in 1924 Scandium-40 (Sc-40 or 40Sc), an isotope of scandium