2-Aminopyridine is an organic compound with the formula H2NC5H4N. It is one of three isomeric aminopyridines. It is a colourless solid that is used in the production of the drugs piroxicam, sulfapyridine, tenoxicam, and tripelennamine. It is produced by the reaction of sodium amide with pyridine, the Chichibabin reaction.
Reactions
Although 2-hydroxypyridine converts significantly to the pyridone tautomer, the related imine tautomer (HNC5H4NH) is less important for 2-aminopyridine.
2-Aminopyridine catalyzes the conversion of maleic anhydride to 2,3-dimethylmaleic anhydride.
Toxicity The acute toxicity is indicated by the = 200 mg/kg (rat, oral).
References
External links MSDS CDC - NIOSH Pocket Guide to Chemical Hazards - 2-Aminopyridine