Louis or Lou Johnson may refer to:
Government and politics E. Louis Johnson (born 1937), American politician, member of the Kentucky House of Representatives Louis A. Johnson (1891–1966), second United States Secretary of Defense Louis P. Johnson (1876–1954), American politician, member of the Minnesota Senate Stanley Johnson (politician) (Louis Stanley Johnson, 1869–1937), English politician
Sports Lou Johnson (1932–2020), American baseball player Lou Johnson (pitcher) (1869–1941), baseball player Dicta Johnson (Louis Johnson, 1887–?), American baseball pitcher Louis Johnson (boxer) (born 1938), American Olympic boxer
Others Louis Johnson (poet) (1924–1988), New Zealand poet Lou Johnson (singer) (1941–2019), American soul singer Louis Johnson (bassist) (1955–2015), American electric bassist Louis Johnson (dancer) (1930–2020), American dancer and choreographer
See also Llew Johnson (born 2000), New Zealand cricketer Louie Johnson (born 2003), English rugby union player Lewis Johnson (disambiguation)