Brazilian submarine Humaitá or Humaytá may refer to one of the following submarines of the Brazilian Navy:
(sometimes also spelled as Humaitá), an Italian launched at La Spezia in 1927; completed and commissioned into the Brazilian Navy in 1929; decommissioned in 1950. , the former American USS Muskallunge (SS-262) launched at Groton, Connecticut, in 1942; acquired by the Brazilian Navy in 1957; returned to the United States Navy in 1968 and subsequently sunk as a target. , a British ordered from Vickers in 1970 and launched at Barrow in 1971; commissioned into the Brazilian Navy in 1973; decommissioned in 1996.
, a Scorpène-class submarine commissioned in 2024.