Ouseley or Ousley is a surname. Notable people with the surname include:

Duncan Ouseley (born 1950), English judge Frederick Ouseley (1825–1889), English musician Gideon Ouseley (1769–1839), Anglo-Irish Methodist Gideon Ouseley, a pseudonym of Oliver St. John Gogarty (1878–1957) Gore Ouseley (1770–1844), British diplomat and linguist Herman Ouseley, Baron Ouseley (born 1945), British politician, author of the Ouseley Report William Ouseley (1769–1842), British orientalist William Gore Ouseley (1797–1866), British diplomat

Ousley Curtis Ousley (1934–1971), American musician Harold Ousley (1929–2015), American jazz musician Ian Ousley (born 2002), American actor

See also Mount Ousley, New South Wales, a suburb of Wollongong Owsley (disambiguation)