E8 may refer to:
Mathematics E8 (mathematics), an exceptional simple Lie group with root lattice of rank 8, or its Lie algebra E8 lattice, special lattice in R8 E8 manifold, mathematical object with no smooth structure or topological triangulation E8 polytope, alternate name for the 421 semiregular (uniform) polytope Elementary abelian group of order 8
Physics E8 Theory, term sometimes loosely used to refer to An Exceptionally Simple Theory of Everything
Transport E-8 Joint STARS, a retired USAF command and control aircraft EMD E8, 1949 diesel passenger train locomotive European route E8, part of the international E-road network, running between Tromsø, Norway and Turku, Finland European walking route E8, a walking route from Ireland to Turkey HMS E8, 1912 British E class submarine London Buses route E8, runs between Ealing Broadway station and Brentford Mikoyan-Gurevich Ye-8, 1962 supersonic jet fighter developed in the Soviet Union E8, IATA code for the former Alpi Eagles airline E8, IATA code for City Airways Spyker E8, Spyker Cars model Hokuriku Expressway, route E8 in Japan East Coast Expressway and Kuala Lumpur–Karak Expressway, route E8 in Malaysia E8 Series Shinkansen, a Japanese high-speed train to be introduced in 2024
Other uses Empire 8, intercollegiate athletic conference affiliated with the NCAA's Division III E-8 (rank), an enlisted rank in the military of the United States E8, baseball scorekeeping abbreviation for an error on the center fielder E8, postcode district in the London E postcode area
See also 8E (disambiguation)