East Lancashire (East Lancs) refers to the eastern part of Lancashire, a ceremonial county in North West England. It can also refer to:

Pennine Lancashire, local government district to be created in 2028, previously referred to as East Lancashire

Health East Lancashire Hospitals NHS Trust East Lancashire Primary Care Trust

Military East Lancashire Regiment, a British Army infantry regiment from 1881 to 1958 East Lancashire Royal Engineers, a British Army unit raised in 1901 42nd (East Lancashire) Infantry Division, formerly called the East Lancashire Division 42nd (East Lancashire) Signal Regiment, a British Army Territorial unit raised in 1908 66th (2nd East Lancashire) Division, a British Army Territorial unit raised in 1914 126th (East Lancashire) Brigade, a British Army unit raised in 1908

Sports East Lancashire Cricket Club, a cricket club in the Lancashire League East Lancashire derby, a football match between Blackburn Rovers F.C. and Burnley F.C. East Lancashire Lions, a rugby league club from Darwen

Transport East Lancashire Coachbuilders, a Blackburn-based manufacturer of bus bodywork East Lancashire line, a railway line between Preston and Colne East Lancashire Railway, a heritage railway line between Bury and Rawtenstall East Lancashire Railway 1844–1859, a 19th-century railway company A580, a major road colloquially known as the East Lancashire Road