José Bonifácio may refer to:
People José Bonifácio de Andrada e Silva (1763–1838), Brazilian poet, statesman and politician José Bonifácio the Younger (1827–1886), Brazilian poet and senator José Bonifácio Lafayette de Andrada (1904–1986), Brazilian politician and former president of the Chamber of Deputies of Brazil
Locations José Bonifácio, São Paulo, a city in São Paulo José Bonifácio (district), a district of São Paulo
Other uses José Bonifácio Esporte Clube, a football club