Arylalkanolamines () are a class of medicinal molecules that are structurally related to one another in certain respects.
Detailed understanding of their structure-activity relationship is expected to aid in drug discovery.
+Phen(Aryl)alkanolamine. All molecules are α-aromatic-alcohols unless stated otherwise. CompoundGroup1/2/3° OHΑ/Β/Γ/ΔΑ/Β/Γ/ΔN Type of Pharmacology PRC0253-OH-2-BN-A 2° γ-aminoalcohol βNHMe2 SN(D)RI PRC200-SS PP-3-A 2° " α,βNHMe NS(D)RI Pridinol " 3° " NC5H10Anticholinergic (NMDA?) Trihexyphenidyl (aka Benzhexol) " " " " " Biperiden""""" BDPCcyclohexanol3°δ-aminoalcoholγ,δNMe2μ/delta-opioid agonist Tramadol " " 3 α-arylalcohol " μ-opioid agonist(prodrug, M1SNRI Venlafaxine " " 2 β-arylalcohol " SNRI Ciramadol " 2° 3 γ-arylalcohol " μ-opioid mixed ant/agonist Phenylpropanolamine PP-2-A 2° 2 NH2 nor/adrenergic releaser Cathine " " " " nor/adrenergic releaser Ephedrine " " β-aminoalcohol NHMe nor/adrenergic releaser Pseudoephedrine " " " " nor/adrenergic releaser Dopamine " " " " endogenous neurotransmitter Epinephrine ArE-2-A " " " neurotransmitter, also a hormone Norepinephrine " " " NH2 neurotransmitter Synephrine " " " " α1 agonist Phenylephrine " " " " α1 agonist Levalbuterol " " " NH(t-Bu) β-agonist Clenbuterol " " " " " Haloperidol Piperidinol 3° δ 4,4 piper DA antagonist Loperamide(Imodium AD)"""""μ-opioid agonist.
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