Southern Freeway may refer to:
Southern Freeway, a freeway in New South Wales, Australia, now known as Princes Motorway Interstate 280 (California), original name Southern Freeway Tabriz Southern Freeway, Turkey Second Southern Highway that crosses Ligang Bridge, Taiwan Southern freeway near Ilz, Styria, Austria Southern Freeway, early name for the B921 Kinglassie Road, Glenrothes, Scotland