Spiller is a German surname meaning player of a musical instrument. It may refer to:
Bill Spiller, American golfer Bill W. Spiller, American broadcaster Billy Spiller, English cricket and rugby player C. J. Spiller, American football player Carlton T. Spiller, American poet Cecil Spiller, Welsh cricketer Charlie Spiller, American football player Cristiano Spiller or Spiller, Italian DJ Danny Spiller, English football player Frederick Spiller, English boxer Gustav Spiller, Hungarian-English writer Henry Spiller, English politician Isaiah Spiller, American football player Letícia Spiller, Brazilian actress Ljerko Spiller, Croatian violinist Mary Spiller, English horticulturist Michael Spiller, American director Neil Spiller, English architect Matthew Spiller, Canadian hockey player Richard Georg Spiller von Hauenschild or Max Waldau, Polish writer Robert Spiller, English politician Teo Spiller, Slovenian artist
Fictional Lucy Spiller, a character from the American TV series Dirt Patrick Spiller, a character from the British TV series Casualty
See also Spiller, Ohio, an unincorporated community in the United States Spiller, the German name of the Polish village Pasiecznik, Lower Silesian Voivodeship Spillers (disambiguation)